Gene name:
    SLC2A2 (GLUT2) ;
    
 
    Protein name:
    Solute carrier family 2, facilitated glucose transporter member 2 ;
    
    Alternative:
    
    Glucose transporter type 2, liver (GLUT-2) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Function:
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Membrane  
      Multi-pass membrane protein 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MTEDKVTGTL |  VFTVITAVLG |  SFQFGYDIGV |  INAPQQVIIS |  HYRHVLGVPL |  
    
 
    100:
    DDRKAINNYV |  INSTDELPTI |  SYSMNPKPTP |  WAEEETVAAA |  QLITMLWSLS |  
    
 
    150:
    VSSFAVGGMT |  ASFFGGWLGD |  TLGRIKAMLV |  ANILSLVGAL |  LMGFSKLGPS |  
    
 
    200:
    HILIIAGRSI |  SGLYCGLISG |  LVPMYIGEIA |  PTALRGALGT |  FHQLAIVTGI |  
    
 
    250:
    LISQIIGLEF |  ILGNYDLWHI |  LLGLSGVRAI |  LQSLLLFFCP |  ESPRYLYIKL |  
    
 
    300:
    DEEVKAKQSL |  KRLRGYDDVT |  KDINEMRKER |  EEASSEQKVS |  IIQLFTNSSY |  
    
 
    350:
    RQPILVALML |  HVAQQFSGIN |  GIFYYSTSIF |  QTAGISKPVY |  ATIGVGAVNM |  
    
 
    400:
    VFTAVSVFLV |  EKAGRRSLFL |  IGMSGMFVCA |  IFMSVGLVLL |  NKFSWMSYVS |  
    
 
    450:
    MIAIFLFVSF |  FEIGPGPIPW |  FMVAEFFSQG |  PRPAALAIAA |  FSNWTCNFIV |  
    
 
    500:
    ALCFQYIADF |  CGPYVFFLFA |  GVLLAFTLFT |  FFKVPETKGK |  SFEEIAAEFQ |  
    
 
    524:
    KKSGSAHRPK |  AAVEMKFLGA |  TETV
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Human
         
        
        Mouse
         
        
        Pig
         
        
        Rat
         
        
        Bovine
         
        
        Chicken
         
        
     
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
    
        Protein for Human Solute carrier family 2, facilitated glucose transporter member 2
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                        
                            "Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein." 
                        
                        
                            Fukumoto H. 
                        ,
                            
Seino S. 
                        ,
                            
Imura H. 
                        ,
                            
Sieno Y. 
                        ,
                            
Eddy R.L. 
                        ,
                            
Fukushima Y. 
                        ,
                            
Byers M.G. 
                        ,
                            
Shows T.B. 
                        ,
                            
Bell G.I. 
                        
                        
                        
                        
                            Proc. Natl. Acad. Sci. U.S.A.85:5434-5438(1988)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LEU-68 
                    
                    
                    tissue :
                    
Kidney . tissue :
                    
Liver .  
             
         
            
        
            
                2.
                
                    
                        
                            "Complete sequencing and characterization of 21,243 full-length human cDNAs." 
                        
                        
                            Ota T. 
                        ,
                            
Suzuki Y. 
                        ,
                            
Nishikawa T. 
                        ,
                            
Otsuki T. 
                        ,
                            
Sugiyama T. 
                        ,
                            
Irie R. 
                        ,
                            
Wakamatsu A. 
                        ,
                            
Hayashi K. 
                        ,
                            
Sato H. 
                        ,
                            
Nagai K. 
                        ,
                            
Kimura K. 
                        ,
                            
Makita H. 
                        ,
                            
Sekine M. 
                        ,
                            
Obayashi M. 
                        ,
                            
Nishi T. 
                        ,
                            
Shibahara T. 
                        ,
                            
Tanaka T. 
                        ,
                            
Ishii S. 
                        ,
                        
                        
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
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                        ,
                            Takahashi M. 
                        ,
                            Kanda K. 
                        ,
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                        ,
                            Furuya T. 
                        ,
                            Kikkawa E. 
                        ,
                            Omura Y. 
                        ,
                            Abe K. 
                        ,
                            Kamihara K. 
                        ,
                            Katsuta N. 
                        ,
                            Sato K. 
                        ,
                            Tanikawa M. 
                        ,
                            Yamazaki M. 
                        ,
                            Ninomiya K. 
                        ,
                            Ishibashi T. 
                        ,
                            Yamashita H. 
                        ,
                            Murakawa K. 
                        ,
                            Fujimori K. 
                        ,
                            Tanai H. 
                        ,
                            Kimata M. 
                        ,
                            Watanabe M. 
                        ,
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                        ,
                            Chiba Y. 
                        ,
                            Ishida S. 
                        ,
                            Ono Y. 
                        ,
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                        ,
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                        ,
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                        ,
                            Hotuta T. 
                        ,
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                        ,
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                        ,
                            Takahashi-Fujii A. 
                        ,
                            Hara H. 
                        ,
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                        ,
                            Nomura Y. 
                        ,
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                        ,
                            Komai F. 
                        ,
                            Hara R. 
                        ,
                            Takeuchi K. 
                        ,
                            Arita M. 
                        ,
                            Imose N. 
                        ,
                            Musashino K. 
                        ,
                            Yuuki H. 
                        ,
                            Oshima A. 
                        ,
                            Sasaki N. 
                        ,
                            Aotsuka S. 
                        ,
                            Yoshikawa Y. 
                        ,
                            Matsunawa H. 
                        ,
                            Ichihara T. 
                        ,
                            Shiohata N. 
                        ,
                            Sano S. 
                        ,
                            Moriya S. 
                        ,
                            Momiyama H. 
                        ,
                            Satoh N. 
                        ,
                            Takami S. 
                        ,
                            Terashima Y. 
                        ,
                            Suzuki O. 
                        ,
                            Nakagawa S. 
                        ,
                            Senoh A. 
                        ,
                            Mizoguchi H. 
                        ,
                            Goto Y. 
                        ,
                            Shimizu F. 
                        ,
                            Wakebe H. 
                        ,
                            Hishigaki H. 
                        ,
                            Watanabe T. 
                        ,
                            Sugiyama A. 
                        ,
                            Takemoto M. 
                        ,
                            Kawakami B. 
                        ,
                            Yamazaki M. 
                        ,
                            Watanabe K. 
                        ,
                            Kumagai A. 
                        ,
                            Itakura S. 
                        ,
                            Fukuzumi Y. 
                        ,
                            Fujimori Y. 
                        ,
                            Komiyama M. 
                        ,
                            Tashiro H. 
                        ,
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                            Nat. Genet.36:40-45(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2) 
                    
                    
                    tissue :
                    
Liver .  
             
         
            
        
            
                3.
                
                    
                        
                            "The DNA sequence, annotation and analysis of human chromosome 3." 
                        
                        
                            Muzny D.M. 
                        ,
                            
Scherer S.E. 
                        ,
                            
Kaul R. 
                        ,
                            
Wang J. 
                        ,
                            
Yu J. 
                        ,
                            
Sudbrak R. 
                        ,
                            
Buhay C.J. 
                        ,
                            
Chen R. 
                        ,
                            
Cree A. 
                        ,
                            
Ding Y. 
                        ,
                            
Dugan-Rocha S. 
                        ,
                            
Gill R. 
                        ,
                            
Gunaratne P. 
                        ,
                            
Harris R.A. 
                        ,
                            
Hawes A.C. 
                        ,
                            
Hernandez J. 
                        ,
                            
Hodgson A.V. 
                        ,
                            
Hume J. 
                        ,
                        
                        
                            Jackson A. 
                        ,
                            Khan Z.M. 
                        ,
                            Kovar-Smith C. 
                        ,
                            Lewis L.R. 
                        ,
                            Lozado R.J. 
                        ,
                            Metzker M.L. 
                        ,
                            Milosavljevic A. 
                        ,
                            Miner G.R. 
                        ,
                            Morgan M.B. 
                        ,
                            Nazareth L.V. 
                        ,
                            Scott G. 
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                            Sodergren E. 
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                            Song X.-Z. 
                        ,
                            Steffen D. 
                        ,
                            Wei S. 
                        ,
                            Wheeler D.A. 
                        ,
                            Wright M.W. 
                        ,
                            Worley K.C. 
                        ,
                            Yuan Y. 
                        ,
                            Zhang Z. 
                        ,
                            Adams C.Q. 
                        ,
                            Ansari-Lari M.A. 
                        ,
                            Ayele M. 
                        ,
                            Brown M.J. 
                        ,
                            Chen G. 
                        ,
                            Chen Z. 
                        ,
                            Clendenning J. 
                        ,
                            Clerc-Blankenburg K.P. 
                        ,
                            Chen R. 
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                            Chen Z. 
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                            Wang J. 
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                            Wang Q. 
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                            Williams G.A. 
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                            Wong G.K.-S. 
                        ,
                            Yao Z. 
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                            Zhang J. 
                        ,
                            Zhang X. 
                        ,
                            Zhao G. 
                        ,
                            Zhou J. 
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                            Zhou Y. 
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                            Gibbs R.A. 
                        
                             
                              more...   
                             
                        
                        
                        
                            Nature440:1194-1198(2006)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                        
                        
                            Mural R.J. 
                        ,
                            
Istrail S. 
                        ,
                            
Sutton G.G. 
                        ,
                            
Florea L. 
                        ,
                            
Halpern A.L. 
                        ,
                            
Mobarry C.M. 
                        ,
                            
Lippert R. 
                        ,
                            
Walenz B. 
                        ,
                            
Shatkay H. 
                        ,
                            
Dew I. 
                        ,
                            
Miller J.R. 
                        ,
                            
Flanigan M.J. 
                        ,
                            
Edwards N.J. 
                        ,
                            
Bolanos R. 
                        ,
                            
Fasulo D. 
                        ,
                            
Halldorsson B.V. 
                        ,
                            
Hannenhalli S. 
                        ,
                            
Turner R. 
                        ,
                        
                        
                            Yooseph S. 
                        ,
                            Lu F. 
                        ,
                            Nusskern D.R. 
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                            Shue B.C. 
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                            Zheng X.H. 
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                            Zhong F. 
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                        ,
                            Venter J.C. 
                        
                             
                              more...   
                             
                        
                        
                            Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 29-100 (ISOFORM 1);VARIANTS LEU-68 AND ILE-110 
                    
                    
                    tissue :
                    
Peripheral blood .  
             
         
            
        
            
                6.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for VARIANT NIDDM ILE-197;VARIANT ILE-110 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for CHARACTERIZATION OF VARIANT NIDDM ILE-197;CHARACTERIZATION OF VARIANT ILE-110 
                    
                    
                 
             
         
            
        
            
                8.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for VARIANT FBS LEU-417 
                    
                    
                 
             
         
            
        
            
                9.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for VARIANTS FBS PRO-389 AND GLU-423